Relationship between histamine release and leukotrienes production from human basophils derived from atopic dermatitis donors.

Basophils are known to release histamine and to produce leukotrienes (LTs) following both IgE-dependent and -independent stimuli. Although there exist a few reports which examined the relationship between histamine release and LTs production, their conclusions were not always in agreement with each other. In the present study, we examined the relationship… CONTINUE READING