Relationship between frontostriatal morphology and executive function deficits in bipolar I disorder following a first manic episode: data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM).

@article{Kozicky2013RelationshipBF,
  title={Relationship between frontostriatal morphology and executive function deficits in bipolar I disorder following a first manic episode: data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM).},
  author={Jan-Marie Kozicky and Tae Ha and Ivan J. Torres and David J. Bond and William Honer and Raymond W Lam and Lakshmi N. Yatham},
  journal={Bipolar disorders},
  year={2013},
  volume={15 6},
  pages={657-68}
}
OBJECTIVES Executive function impairments are a core feature of bipolar I disorder (BD-I), not only present during acute episodes but also persisting following remission of mood symptoms. Despite advances in knowledge regarding the neural basis of executive functions in healthy subjects, research into morphological abnormalities underlying the deficits in BD-I is lacking. METHODS Patients with BD-I within three months of sustained remission from their first manic episode (n = 41) underwent… CONTINUE READING
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