Relationship between free iron and glycated hemoglobin in uncontrolled type 2 diabetes patients associated with complications

@article{Shetty2008RelationshipBF,
  title={Relationship between free iron and glycated hemoglobin in uncontrolled type 2 diabetes patients associated with complications},
  author={J. Shetty and M. Prakash and Mohammad Ibrahim},
  journal={Indian Journal of Clinical Biochemistry},
  year={2008},
  volume={23},
  pages={67-70}
}
Free iron in serum has been found in several disease conditions including diabetes. In the present work, we studied the relationship between free iron, fasting blood glucose (FBG) and glycated haemoglobin (HbA1c). Study was carried out on 50 type 2 diabetes cases under poor glycemic control associated with complications, 53 type 2 diabetes cases under good glycemic control and 40 healthy controls. We estimated free iron, both ferrous (Fe+2) and ferric (Fe+3) form, protein thiols, lipid… Expand
Correlation between serum ferritin and glycaemic control in patients of type 2 diabetes mellitus: a case control study
TLDR
There is a positive association between elevated iron stores measured by serum ferritin levels and type 2 diabetes mellitus and the influence of body iron stores on HbA1c and blood glucose. Expand
EVALUATION OF SERUM-FREE IRON AND GLYCATED HEMOGLOBIN IN UNCONTROLLED TYPE-II DIABETIC PATIENTS
TLDR
The elevated serum free iron in uncontrolled diabetes may contribute to oxidative stress which may be associated with complications of diabetes. Expand
CORRELATION BETWEEN SERUM FERRITIN AND GLYCEMIC CONTROL IN PATIENTS OF TYPE 2 DIABETES MELLITUS
TLDR
Diabetics have elevated ferritin levels which correlate with their glycemic status (HbA1c, FBS, PPBS) and it may thus be used as a marker for glycemic control in diabetes. Expand
Elevated Serum ferritin and Serum Free Iron-A novel marker for prediabetes Type 2 in relationship with HbA 1 c
Diabetes mellitus (DM) comprises a group of common metabolic disorders that share common phenotype of hyperglycemia. Understanding the pathogenesis and preventing long-term complications have beenExpand
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TLDR
Study shows elevated ferritin level was found in the patients suffering from type 2 diabetes mellitus, and Elevated iron stores are also associated with Total Cholesterol and Triglycerides. Expand
Serum Free Iron Concentration in Patients with Type 2 Diabetes Mellitus with Good and Poor Control and Its Correlation with Glycemic Control
TLDR
Serum free iron concentration was higher in patients with type 2 diabetes mellitus with poor control and there was a positive correlat ion with seru m freeIron concentration and glycemic control, suggesting important role of iron in metabolic derangement in diabetic patients and its complications. Expand
Study of Serum Ferritin and its relation with Glycemic control in Type 2 Diabetes Mellitus
TLDR
Estimation of serum Ferritin may be useful in screening diabetics with poor glycemic control who are at high risk of developing complications and can be one of the adjuvant aids in investigations which guides in taking timely medical intervention and preventing further progression of disease. Expand
Ferritin and serum iron as surrogate markers of poor glycemic control and microvascular complications in type 2 diabetes mellitus
TLDR
Results were consistent with the hypothesis that high iron indices (serum iron and serum ferritin) not high enough to cause hemochromatosis but were still associated with poor glycemic control and its complications among patients with type 2 DM. Expand
A STUDY ON RELATIONSHIP BETWEEN FASTING PLASMA GLUCOSE, COPPER AND CERULOPLASMIN LEVELS IN TYPE 2 DIABETES MELLITUS
TLDR
An increase in copper and FPG with decreased levels of ceruloplasmin which may be due to generation of ROS which leads to increased consumption of available antioxidants in the body. Expand
Glycemic control, micronutrients and some metabolic enzyme activity in type 2 diabetes
TLDR
Diabetes may alter the metabolism of vitamin C, Iron, calcium and phosphorus while poor glycemic control may be associated with changes in calcium and LDH activity. Expand
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