Relationship between food intake and metabolic rate in rats treated with beta-adrenoceptor agonists.

@article{Yamashita1994RelationshipBF,
  title={Relationship between food intake and metabolic rate in rats treated with beta-adrenoceptor agonists.},
  author={Junsuke Yamashita and T Onai and David A. York and George A. Bray},
  journal={International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity},
  year={1994},
  volume={18 6},
  pages={429-33}
}
The purpose of the present experiment was to clarify the interaction between food intake and activity of the thermogenic component of the sympathetic nervous system by studying the dose response relationships of typical beta 1-, beta 2-, and beta 3-adrenoceptor agonists on oxygen consumption and food intake. The data showed that the ED50 for the effects of Dobutamine (beta 1), Clenbuterol (beta 2) and ICI D7114 (beta 3) agonists on food intake were 8.9, 0.041 and > 1.1 mumol/kg respectively… CONTINUE READING

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