Relationship between fentanyl dosage and immune function in the postoperative period.

@article{Yardeni2008RelationshipBF,
  title={Relationship between fentanyl dosage and immune function in the postoperative period.},
  author={Israel Zeev Yardeni and Benzion Beilin and Eduard Mayburd and Yifat Alcalay and Hanna Bessler},
  journal={Journal of opioid management},
  year={2008},
  volume={4 1},
  pages={27-33}
}
BACKGROUND Anesthesia and surgery are associated with impairment of the immune system expressed as an excessive proinflammatory immune response and suppression of cell mediated immunity. Opioids, an integral part of anesthetic technique, possess an inhibitory effect on both humoral and cellular immune responses. It was the aim of the present study to examine the effect of various doses of fentanyl on cytokine production during the perioperative period. INTERVENTION The effect of large (LDFA… CONTINUE READING