Relationship between exhaled nitric oxide and airway hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects.

@article{Gouw1998RelationshipBE,
  title={Relationship between exhaled nitric oxide and airway hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects.},
  author={H W de Gouw and Katharina Gruenberg and Robert Schot and Aloys C. M. Kroes and E. C. Dick and Peter J. Sterk},
  journal={The European respiratory journal},
  year={1998},
  volume={11 1},
  pages={126-32}
}
Exhaled nitric oxide (NO) is elevated in asthmatics, and varies with disease severity. We postulated that a respiratory virus infection increases exhaled NO levels in asthma, and examined the relationship between the virus-induced changes in exhaled NO and in airway hyperresponsiveness to histamine. In a parallel study, seven patients underwent experimental… CONTINUE READING