Relationship between epicardial ST-segment elevation and myocardial ischemic damage after experimental coronary artery occlusion in dogs.

@article{Heng1976RelationshipBE,
  title={Relationship between epicardial ST-segment elevation and myocardial ischemic damage after experimental coronary artery occlusion in dogs.},
  author={Ming K. Heng and Bramah N. Singh and Robin M Norris and Manorama John and R. Stephen Elliot},
  journal={The Journal of clinical investigation},
  year={1976},
  volume={58 6},
  pages={1317-26}
}
The relationship between early and late epicardial electrocardiographic changes as well as those in regional myocardial blood flow (MBF) and the severity of myocardial damage was determined in 12 anesthetized dogs with left anterior descending coronary artery ligation. Radioactive microspheres (15 mum) were used to measure regional MBF at 15 min (early) and 24 h (late) after coronary occlusion. Severity of myocardial damage was assessed by the extent of myocardial creatine phosphokinase… CONTINUE READING

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