Relationship between depression and frailty in older adults: A systematic review and meta-analysis

@article{Soysal2017RelationshipBD,
  title={Relationship between depression and frailty in older adults: A systematic review and meta-analysis},
  author={Pınar Soysal and Nicola Veronese and Trevor Thompson and Kai G. Kahl and Brisa Fernandes and A. Matthew Prina and Marco Solmi and Patricia Schofield and Ai Koyanagi and Ping-Tao Tseng and Pao-Yao Lin and Che-Sheng Chu and Theodore D. Cosco and Matteo Cesari and Andr{\'e} Ferrer Carvalho and Brendon Stubbs},
  journal={Ageing Research Reviews},
  year={2017},
  volume={36},
  pages={78-87}
}
View on Elsevier
repositorio.ufc.br
297 Citations
Highly Influential Citations
3
Background Citations
81
Methods Citations
4
Results Citations
12

Figures and Tables from this paper

297 Citations

Citation Type

Citation Type

Title: Relationship between depression and frailty in older adults: A systematic review and meta-analysis Authors:
TLDR
A systematic review and meta-analysis of crosssectional/longitudinal studies investigating depression and frailty found that the relationships between these entities are unclear, but the strength of the reciprocal associations between frailty and depression was assessed.
Is living alone a risk factor of frailty? A systematic review and meta-analysis
Could Frailty be an Explanatory Factor of the Association between Depression and Other Geriatric Syndromes in Later Life?
TLDR
Among depressed patients, frailty may be hypothesized as a causal pathway toward adverse health outcomes associated with depression, and should be treated or prevented in order to minimize the impact of other geriatric syndromes among depressed older adults.
Depression in frail older adults: Associations and gender difference
TLDR
Depression may play a key role in the development of frailty in both genders, and depressed men seem to be at a higher risk than women for development ofFrailty are, physical activity and strength measures in the FRIED criteria had a high impact in women for depressive symptoms.
Association Between Frailty-Related Factors and Depression among Older Adults
TLDR
The associations between individual frailty-related factors and depression differed among males and females and may help elucidate specific targets to be prioritized for clinical assessment and intervention.
Frailty, depression risk and 10-year hospitalization in older adults. The FRADEA study.
Depressive symptoms are associated with incident frailty in a Chinese population: the Rugao Longevity and Aging Study
TLDR
Depressive symptoms are associated with prevalent and incident frailty in Chinese older population and together with the observations of the European populations, depressive symptoms may be a candidate risk factor of frailty.
Depression as a determinant of frailty in late life
TLDR
Late life depression and frailty are associated in a dose-dependent manner, irrespective of the used definitions, and future research on underlying biological mechanisms should preferably be based on formal psychiatric diagnoses and objectively assessment frailty status.
Bidirectional relationship between insomnia and frailty in older adults: A 2-year longitudinal study.
Prevalence of Frailty and Associated Factors Among Hospitalized Older Adults: A Cross-Sectional Study.
TLDR
It was found that the prevalence of frailty among hospitalized older adults was 39.7%.
...
...

References

SHOWING 1-10 OF 72 REFERENCES
Inflammation and frailty in the elderly: A systematic review and meta-analysis
Depression and frailty in later life: a systematic review
TLDR
Measurement variability of depressive symptomatology and inclusion of older adults who are severely depressed, have cognitive impairment or dementia, or stroke may confound the frailty syndrome with single disease outcomes, accounting for a substantial proportion of shared variance in the syndromes.
The relationship between depression and frailty syndrome: a systematic review
TLDR
Depression and frailty occur in a significant proportion of frail older individuals and studies on the causal relationship between the two syndromes are clearly necessary in the future.
Depression, frailty, and all-cause mortality: a cohort study of men older than 75 years.
Depression and Frailty in Late Life: Evidence for a Common Vulnerability.
  • M. Lohman, L. Dumenci, B. Mezuk
  • Psychology, Medicine
    The journals of gerontology. Series B, Psychological sciences and social sciences
  • 2016
TLDR
Results indicate that the correlation of frailty and depression in late life is substantial, and the association between the two constructs cannot be fully explained by symptom overlap, suggesting that psychological vulnerability may be an important component of frailt.
Are depression and frailty overlapping syndromes in mid- and late-life? A latent variable analysis.
  • B. Mezuk, M. Lohman, L. Dumenci, K. Lapane
  • Psychology, Medicine
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
  • 2013
Exercise for depression in older adults: a meta-analysis of randomized controlled trials adjusting for publication bias.
TLDR
adjusting for publication bias increased the beneficial effects of exercise in three subgroup analysis, suggesting that previous meta-analyses have underestimated the benefits of exercise due to publication bias.
Frailty predicts new and persistent depressive symptoms among community-dwelling older adults: findings from Singapore longitudinal aging study.
Prevalence of frailty and factors associated with frailty in the elderly population of Lleida, Spain: the FRALLE survey.
Frailty and depression in older adults: a high-risk clinical population.
  • Patrick J. Brown, S. Roose, K. Avlund
  • Medicine, Psychology
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
  • 2014
...
...