Relationship between depression and frailty in older adults: A systematic review and meta-analysis

@article{Soysal2017RelationshipBD,
  title={Relationship between depression and frailty in older adults: A systematic review and meta-analysis},
  author={Pınar Soysal and Nicola Veronese and Trevor Thompson and Kai G. Kahl and Brisa Fernandes and A. Matthew Prina and Marco Solmi and Patricia Schofield and Ai Koyanagi and Ping-Tao Tseng and Pao-Yao Lin and Che-Sheng Chu and Theodore D. Cosco and Matteo Cesari and Andr{\'e} Ferrer Carvalho and Brendon Stubbs},
  journal={Ageing Research Reviews},
  year={2017},
  volume={36},
  pages={78-87}
}
View on Elsevier
repositorio.ufc.br
311 Citations
Highly Influential Citations
4
Background Citations
86
Methods Citations
4
Results Citations
14

Figures and Tables from this paper

311 Citations

Title: Relationship between depression and frailty in older adults: A systematic review and meta-analysis Authors:
TLDR
A systematic review and meta-analysis of crosssectional/longitudinal studies investigating depression and frailty found that the relationships between these entities are unclear, but the strength of the reciprocal associations between frailty and depression was assessed.
Is living alone a risk factor of frailty? A systematic review and meta-analysis
Could Frailty be an Explanatory Factor of the Association between Depression and Other Geriatric Syndromes in Later Life?
TLDR
Among depressed patients, frailty may be hypothesized as a causal pathway toward adverse health outcomes associated with depression, and should be treated or prevented in order to minimize the impact of other geriatric syndromes among depressed older adults.
Depression in frail older adults: Associations and gender difference
TLDR
Depression may play a key role in the development of frailty in both genders, and depressed men seem to be at a higher risk than women for development ofFrailty are, physical activity and strength measures in the FRIED criteria had a high impact in women for depressive symptoms.
Association Between Frailty-Related Factors and Depression among Older Adults
TLDR
The associations between individual frailty-related factors and depression differed among males and females and may help elucidate specific targets to be prioritized for clinical assessment and intervention.
Frailty, depression risk and 10-year hospitalization in older adults. The FRADEA study.
Frailty, depression and mortality in a cohort of community-dwelling older adults
TLDR
Combinations between frailty and depression can result in differences in survival and mortality among older adults, and depression proved to be the ordering variable of the groups in relation to risk estimates, even in the presence of important covariates.
Depression as a determinant of frailty in late life
TLDR
Late life depression and frailty are associated in a dose-dependent manner, irrespective of the used definitions, and future research on underlying biological mechanisms should preferably be based on formal psychiatric diagnoses and objectively assessment frailty status.
Bidirectional relationship between insomnia and frailty in older adults: A 2-year longitudinal study.
Is Sensory Loss an Understudied Risk Factor for Frailty? A Systematic Review and Meta-analysis.
TLDR
A systematic review and meta-analysis of cross-sectional associations between VI/HI with pre-frailty and frailty and highlights knowledge gaps on the directionality and modifiability of these relationships and the impact of SI/TI and multiple sensory impairments on frailty.
...
...

References

SHOWING 1-10 OF 73 REFERENCES
Depression and frailty in later life: a systematic review
TLDR
Measurement variability of depressive symptomatology and inclusion of older adults who are severely depressed, have cognitive impairment or dementia, or stroke may confound the frailty syndrome with single disease outcomes, accounting for a substantial proportion of shared variance in the syndromes.
The relationship between depression and frailty syndrome: a systematic review
TLDR
Depression and frailty occur in a significant proportion of frail older individuals and studies on the causal relationship between the two syndromes are clearly necessary in the future.
Depression, frailty, and all-cause mortality: a cohort study of men older than 75 years.
Depression and Frailty in Late Life: Evidence for a Common Vulnerability.
  • M. LohmanL. DumenciB. Mezuk
  • Psychology, Medicine
    The journals of gerontology. Series B, Psychological sciences and social sciences
  • 2016
TLDR
Results indicate that the correlation of frailty and depression in late life is substantial, and the association between the two constructs cannot be fully explained by symptom overlap, suggesting that psychological vulnerability may be an important component of frailt.
Are depression and frailty overlapping syndromes in mid- and late-life? A latent variable analysis.
  • B. MezukM. LohmanL. DumenciK. Lapane
  • Psychology, Medicine
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
  • 2013
Frailty predicts new and persistent depressive symptoms among community-dwelling older adults: findings from Singapore longitudinal aging study.
Exercise for depression in older adults: a meta-analysis of randomized controlled trials adjusting for publication bias
TLDR
It is advocated that exercise be considered as a routine component of the management of depression in older adults, suggesting that previous meta-analyses have underestimated the benefits of exercise due to publication bias.
Prevalence of frailty and factors associated with frailty in the elderly population of Lleida, Spain: the FRALLE survey.
Frailty and depression in older adults: a high-risk clinical population.
  • Patrick J. BrownS. Roose K. Avlund
  • Medicine, Psychology
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
  • 2014
Physical frailty: vulnerability of patients suffering from late-life depression
TLDR
A quarter of depressed older patients is physically frail, especially the most depressed group, and this cannot be explained by overlap in criteria and should be examined in future studies, primarily on its presumed clinical relevance.
...
...