Relationship between cortisone and muscle work in determining muscle size.

@article{Goldberg1969RelationshipBC,
  title={Relationship between cortisone and muscle work in determining muscle size.},
  author={Alfred L Goldberg and H. M. Goodman},
  journal={The Journal of physiology},
  year={1969},
  volume={200 3},
  pages={667-75}
}
1. Large doses of cortisone caused marked atrophy of the plantaris muscle and other pale muscles of hind limbs of hypophysectomized rats, but hormone treatment had little effect on the size of the red soleus muscle.2. Denervation increased the sensitivity of the soleus and plantaris to the catabolic effects of cortisone.3. Increased work induced by tenotomy of the synergistic gastrocnemius made the plantaris muscle less sensitive to cortisone-induced atrophy.4. Since the catabolic effects of… CONTINUE READING
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