Relationship between chronic tadalafil administration and improvement of endothelial function in men with erectile dysfunction: a pilot study

@article{Aversa2007RelationshipBC,
  title={Relationship between chronic tadalafil administration and improvement of endothelial function in men with erectile dysfunction: a pilot study},
  author={Antonio Aversa and Elena Greco and Roberto Bruzziches and Marcello Pili and Giuseppe M.C. Rosano and Giovanni Spera},
  journal={International Journal of Impotence Research},
  year={2007},
  volume={19},
  pages={200-207}
}
Men with erectile dysfunction (ED) frequently have a disproportionate burden of comorbid vascular disorders including atherosclerotic disease. We investigated whether scheduled tadalafil is better than on-demand (OD) in improving endothelium-dependent vasodilatation of cavernous arteries in men with ED and whether this effect is also exerted on markers of endothelial function. We did an open-label, randomized, crossover study including 20 male outclinic patients aged 18 years or older (mean age… CONTINUE READING

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