Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations.

@article{Patel2002RelationshipBB,
  title={Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations.},
  author={Irem S Patel and Terence A.R. Seemungal and M Wilks and Simon J Lloyd-Owen and Gavin C Donaldson and Jagwiga A Wedzicha},
  journal={Thorax},
  year={2002},
  volume={57 9},
  pages={759-64}
}
BACKGROUND Patients with chronic obstructive pulmonary disease (COPD) are prone to frequent exacerbations which are a significant cause of morbidity and mortality. Stable COPD patients often have lower airway bacterial colonisation which may be an important stimulus to airway inflammation and thereby modulate exacerbation frequency. METHODS Twenty nine patients with COPD (21 men, 16 current smokers) of mean (SD) age 65.9 (7.84) years, forced expiratory volume in 1 second (FEV(1)) 1.06 (0.41… CONTINUE READING

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