Relationship between age at onset and magnetic resonance image-defined hyperintensities in mood disorders.

@article{Takahashi2008RelationshipBA,
  title={Relationship between age at onset and magnetic resonance image-defined hyperintensities in mood disorders.},
  author={Katsunori Takahashi and Akihiko Oshima and Itsuro Ida and Hiroshi Kumano and Naoya Yuuki and Masato Fukuda and Makoto Amanuma and Keigo Endo and Masahiko Mikuni},
  journal={Journal of psychiatric research},
  year={2008},
  volume={42 6},
  pages={443-50}
}
OBJECTIVES To examine in patients with mood disorders the relationship of age at onset with the location and degree of MRI-defined brain hyperintensities. METHOD Fifty-two patients diagnosed as having mood disorders and 14 controls participated in the study. Brain MR images were analyzed according to semiquantitative ratings for the anatomical distribution and severity of T2-weighted hyperintensities. We compared these hyperintensities among the three age- and sex-matched groups of late-onset… CONTINUE READING