Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophrenia.

@article{Fanous2005RelationshipBA,
  title={Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophrenia.},
  author={Ayman H. Fanous and Edwin J. C. G. van den Oord and Brien P. Riley and Steven H. Aggen and Michael C. Neale and Francis Anthony O'Neill and Dermot Walsh and Kenneth S. Kendler},
  journal={The American journal of psychiatry},
  year={2005},
  volume={162 10},
  pages={1824-32}
}
OBJECTIVE The purpose of this study was to determine whether a haplotype in the dystrobrevin binding protein 1 (DTNBP1) gene previously associated with schizophrenia not only increases the susceptibility to psychotic illness but also to a more or less clinically specific form of psychotic illness. METHOD In the Irish Study of High-Density Schizophrenia Families, subjects with psychotic illness (N=755) were given lifetime ratings of clinical features according to the Operational Criteria… CONTINUE READING

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