Relationship between Measures of HIV Reactivation and Decline of the Latent Reservoir under Latency-Reversing Agents.

@article{Petravic2017RelationshipBM,
  title={Relationship between Measures of HIV Reactivation and Decline of the Latent Reservoir under Latency-Reversing Agents.},
  author={Janka Petravic and Thomas Aagaard Rasmussen and Sharon R. Lewin and Stephen J Kent and Miles P. Davenport},
  journal={Journal of virology},
  year={2017},
  volume={91 9}
}
Antiretroviral-free HIV remission requires substantial reduction of the number of latently infected cells and enhanced immune control of viremia. Latency-reversing agents (LRAs) aim to eliminate latently infected cells by increasing the rate of reactivation of HIV transcription, which exposes these cells to killing by the immune system. As LRAs are explored in clinical trials, it becomes increasingly important to assess the effect of an increased HIV reactivation rate on the decline of latently… CONTINUE READING