Relationship between HIV coreceptor tropism and disease progression in persons with untreated chronic HIV infection.

@article{Goetz2009RelationshipBH,
  title={Relationship between HIV coreceptor tropism and disease progression in persons with untreated chronic HIV infection.},
  author={Matthew Bidwell Goetz and Robert E Leduc and Jay R. Kostman and Ann M. Labriola and Yolanda Lie and Jodi Marie Weidler and Eoin Coakley and Michael C Bates and Roberta Luskin-Hawk},
  journal={Journal of acquired immune deficiency syndromes},
  year={2009},
  volume={50 3},
  pages={259-66}
}
OBJECTIVE To assess the effect of HIV coreceptor tropism (CRT) on the relative risk of progression to a composite outcome of CD4 count < or =350 cells per microliter, treatment initiation, or death. METHODS CRT assays were performed after study closure in baseline samples obtained from enrollees in a prospectively monitored cohort of treatment-naive adults with > or =450 CD4 cells per microliter and > or =1000 HIV-1 RNA copies per milliliter. RESULTS Dual/mixed (D/M) and R5 CRT were… CONTINUE READING
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