Relationship between Escherichia coli growth rate and bacterial susceptibility to ciprofloxacin.

Abstract

The effect of Escherichia coli growth rate on its susceptibility to ciprofloxacin was investigated using bacteria grown on different carbon sources and harboring mutations in genes encoding tricarboxylic acid cycle enzymes. A 1-h treatment of the wild type (wt) grown on glucose, succinate, malate, α-ketoglutarate or acetate with 0.3 μg ml-1 ciprofloxacin… (More)
DOI: 10.1093/femsle/fnx254

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