Corpus ID: 87376552

Relationship between DNA repair and drug resistance of tumors

  title={Relationship between DNA repair and drug resistance of tumors},
  author={Zhang Ji-hong},
  • Zhang Ji-hong
  • Published 2012
  • Biology
  • chemotherapy is a common treatment for cancer,but its natural and acquired resistance is a serious problem that limits its clinical application.The change of DNA repair ability of cancer cells is one of the reasons which cause resistance to chemotherapeutic agents.DNA repair system is the main factor to maintain the genome stability,usually several repair pathways are involved in the chemotherapeutics efficacy.Therefore,it is important to understand the relationship between DNA repair and… CONTINUE READING

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