Relationship among circulating tumor cells, CEA and overall survival in patients with metastatic colorectal cancer.

@article{Aggarwal2013RelationshipAC,
  title={Relationship among circulating tumor cells, CEA and overall survival in patients with metastatic colorectal cancer.},
  author={C Er. Harisharan Aggarwal and Neal J. Meropol and Cornelis J. A. Punt and Nicholas O Iannotti and Bruce H. Saidman and Kert D. Sabbath and Nashat Y. Gabrail and Joel Picus and Michael Andew Morse and Edith P. Mitchell and Matthew C. Miller and Steven A. Cohen},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2013},
  volume={24 2},
  pages={
          420-8
        }
}
BACKGROUND We previously reported results of a prospective trial evaluating the significance of circulating tumor cells (CTCs) in patients with metastatic colorectal cancer (mCRC). This secondary analysis assessed the relationship of the CTC number with carcinoembryonic antigen (CEA) and overall survival. PATIENTS AND METHODS Patients with mCRC had CTCs measured at baseline and specific time points after the initiation of new therapy. Patients with a baseline CEA value ≥ 10 ng/ml and CEA… CONTINUE READING
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