Relationship Between Plasma Sialic Acid Concentration and Microvascular and Macrovascular Complications in Type 1 Diabetes

@inproceedings{2001RelationshipBP,
  title={Relationship Between Plasma Sialic Acid Concentration and Microvascular and Macrovascular Complications in Type 1 Diabetes},
  author={},
  year={2001}
}
  • Published 2001
DIABETES CARE, VOLUME 24, NUMBER 2, FEBRUARY 2001 The serum or plasma sialic acid (N-acetyl neuraminic acid) concentration is a marker of the acute-phase response, since many of the acute-phase proteins (e.g., a1-acid glycoprotein, fibrinogen, and haptoglobin) are glycoproteins, with sialic acid as the terminal sugar of the oligosaccharide chain (1). An elevated serum sialic acid level is a strong predictor of cardiovascular mortality in the general population (2). In type 2 diabetes, the… CONTINUE READING