Relationship Between Gastric Disease and Deletion of cag Pathogenicity Island Genes of Helicobacter pylori in Gastric Juice

@article{Kawamura2003RelationshipBG,
  title={Relationship Between Gastric Disease and Deletion of cag Pathogenicity Island Genes of Helicobacter pylori in Gastric Juice},
  author={Osamu Kawamura and Masami Murakami and Osamu Araki and Takuro Yamada and Sayaka Tomizawa and Yasuyuki Shimoyama and Keiko Minashi and Masaki Maeda and Motoyasu Kusano and Masatomo Mori},
  journal={Digestive Diseases and Sciences},
  year={2003},
  volume={48},
  pages={47-53}
}
The cag pathogenicity island genes of Helicobacter pylori (ie, cag1, cag5, cagT, cagE, and cagA) were detected by PCR in DNA extracted from endoscopically collected gastric juice, and the relationship between these genes and gastric disease was studied in 25 patients with early gastric cancer, 9 patients with gastric ulcer, and 15 patients with chronic active gastritis. In three patients with early gastric cancer and one patient with gastric ulcer, cag pathogenicity island genes were amplified… CONTINUE READING
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