• DOI:10.1023/A:1018854107623
Corpus ID: 20950168

Relationship Between Changes of Active Oxygen Metabolism and Blood Flow and Formation, Progression, and Recovery of Lesions in Gastric Mucosa of Rats with a Single Treatment of Compound 48/80, a Mast Cell Degranulator

@article{Ohta2004RelationshipBC,
  title={Relationship Between Changes of Active Oxygen Metabolism and Blood Flow and Formation, Progression, and Recovery of Lesions in Gastric Mucosa of Rats with a Single Treatment of Compound 48/80, a Mast Cell Degranulator},
  author={Y. Ohta and T. Kobayashi and K. Nishida and I. Ishiguro},
  journal={Digestive Diseases and Sciences},
  year={2004},
  volume={42},
  pages={1221-1232}
}

Y. Ohta, T. Kobayashi, +1 author I. Ishiguro

Published 2004

Biology, Medicine

Digestive Diseases and Sciences

The relationship between the changes of activeoxygen metabolism and blood flow and the formation,progression, and recovery of lesions was examined in thegastric mucosa of rats treated once with compound 48/80, a mast cell degranulator. Gastricmucosal lesions appeared 0.5 hr after compound 48/80treatment, became worst at 3 hr, and recovered fairlywell at 12 hr. Increases in gastric mucosal lipidperoxide content and xanthine oxidase andmyeloperoxidase activities and decreases in gastricmucosal… CONTINUE READING

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