Relationship Between β-Amyloid and Mitochondrial Dynamics

  title={Relationship Between β-Amyloid and Mitochondrial Dynamics},
  author={Dah Ihm Kim and Ki Hoon Lee and Ji Young Oh and Jun Sung Kim and Ho Jae Han},
  journal={Cellular and Molecular Neurobiology},
Mitochondria as dynamic organelles undergo morphological changes through the processes of fission and fusion which are major factors regulating their functions. A disruption in the balance of mitochondrial dynamics induces functional disorders in mitochondria such as failed energy production and the generation of reactive oxygen species, which are closely related to pathophysiological changes associated with Alzheimer’s disease (AD). Recent studies have demonstrated a relationship between… CONTINUE READING