Relations of thyroid function to body weight: cross-sectional and longitudinal observations in a community-based sample.

  title={Relations of thyroid function to body weight: cross-sectional and longitudinal observations in a community-based sample.},
  author={Caroline S. Fox and Michael J. Pencina and Ralph B. D'Agostino and Joanne M. Murabito and Ellen W. Seely and Elizabeth N. Pearce and Ramachandran S. Vasan},
  journal={Archives of internal medicine},
  volume={168 6},
BACKGROUND Overt hypothyroidism and hyperthyroidism may be associated with weight gain and loss. We assessed whether variations in thyroid function within the reference (physiologic) range are associated with body weight. METHODS Framingham Offspring Study participants (n=2407) who attended 2 consecutive routine examinations, were not receiving thyroid hormone therapy, and had baseline serum thyrotropin (TSH) concentrations of 0.5 to 5.0 mIU/L and follow-up concentrations of 0.5 to 10.0 mIU/L… 

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