Relations between eNOS Glu298Asp polymorphism and progression of diabetic nephropathy.

@article{Shin2004RelationsBE,
  title={Relations between eNOS Glu298Asp polymorphism and progression of diabetic nephropathy.},
  author={Young Shin Shin and Sang Hong Baek and Ki Yuk Chang and Cheol Whee Park and Chul Woo Yang and Dong Chan Jin and Yong Soo Kim and Yoon Sik Chang and Byung Kee Bang},
  journal={Diabetes research and clinical practice},
  year={2004},
  volume={65 3},
  pages={257-65}
}
BACKGROUND Nitric oxide (NO) is related to the pathogenesis of renal hemodynamics in diabetes mellitus. Endothelial nitric oxide synthase (eNOS) gene polymorphism is considered the deterioration factor for progressive renal disease. It has been reported that an interaction of angiotensin II (Ang II) and NO is involved in the control of glomerular hemodynamics. This study aimed to elucidate the roles of eNOS and the angiotensin-converting enzyme (ACE) gene polymorphism for the progression of… CONTINUE READING

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