Relation of type 2 diabetes to individual admixture and candidate gene polymorphisms in the Hispanic American population of San Luis Valley, Colorado.

@article{Parra2004RelationOT,
  title={Relation of type 2 diabetes to individual admixture and candidate gene polymorphisms in the Hispanic American population of San Luis Valley, Colorado.},
  author={Eteban J Parra and Clive J. Hoggart and Carolina Bonilla and Sonia Dios and Jill M Norris and J. Andrew Marshall and Richard F. Hamman and Robert E. Ferrell and Paul McKeigue and Mark D. Shriver},
  journal={Journal of medical genetics},
  year={2004},
  volume={41 11},
  pages={e116}
}
T he prevalence of type 2 diabetes is higher in populations of Native American ancestry, and in Hispanic American populations formed by admixture between Europeans and Native Americans, than in populations of European ancestry. One approach to distinguishing between environmental and genetic explanations for this difference is to study the relationship of type 2 diabetes risk to individual admixture proportions (the proportions of an individual’s genome that are of European and Native American… CONTINUE READING

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Candidate gene association study in type 2 diabetes indicates a role for genes involved in b - cell function as well as insulin action

  • W Siffert, D Rosskopf, +8 authors B Horsthemke
  • PLoS Biol
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