Relation of gastric secretory response in man to dose of insulin.

The relation between dose of insulin and gastric secretion of acid and pepsin was studied in 5 healthy adult men. Doses of insulin ranged from 0.025 to 0.4 unit per kg intravenously. The peak 15-min acid output increased with increasing insulin dose up to a maximum observed response with 0.2 unit per kg; 0.4 unit per kg did not produce a higher peak… (More)