Relation of cord plasma concentrations of proinsulin, 32-33 split proinsulin, insulin and C-peptide to placental weight and the baby's size and proportions at birth.

Abstract

Small and disproportionate size at birth are associated with type 2 diabetes and coronary heart disease in adult life. Insulin has an important role in controlling growth in utero and we hypothesised that reduced fetal insulin secretion could be one factor underlying these associations. We therefore measured cord plasma concentrations of proinsulin, 32-33… (More)

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@article{Godfrey1996RelationOC, title={Relation of cord plasma concentrations of proinsulin, 32-33 split proinsulin, insulin and C-peptide to placental weight and the baby's size and proportions at birth.}, author={Kathryn M. Godfrey and C. Hales and C. B. Osmond and D. J. Barker and Katia Taylor}, journal={Early human development}, year={1996}, volume={46 1-2}, pages={129-40} }