Relation of contraceptive and reproductive history to ovarian cancer risk in carriers and noncarriers of BRCA1 gene mutations.

@article{McGuire2004RelationOC,
  title={Relation of contraceptive and reproductive history to ovarian cancer risk in carriers and noncarriers of BRCA1 gene mutations.},
  author={Valerie A McGuire and Anna Felberg and Moyra Mills and Kimberly Laskie Ostrow and Richard. dicioccio and Esther M John and Dee W. West and Alice S. Whittemore},
  journal={American journal of epidemiology},
  year={2004},
  volume={160 7},
  pages={613-8}
}
In the general population, ovarian cancer risk is inversely associated with oral contraceptive use, tubal ligation, and childbearing. Among carriers of BRCA1 gene mutations, the data are conflicting. The authors identified women diagnosed with incident invasive epithelial ovarian cancer in the San Francisco Bay Area of California from March 1997 through July 2001. They compared the contraceptive and reproductive histories of 36 carrier cases and 381 noncarrier cases with those of 568 controls… CONTINUE READING

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