• DOI:10.1212/01.wnl.0000271087.67782.cb
Corpus ID: 14751953

Relation of cognitive activity to risk of developing Alzheimer disease

@article{Wilson2007RelationOC,
  title={Relation of cognitive activity to risk of developing Alzheimer disease},
  author={R. Wilson and P. Scherr and J. Schneider and Y. Tang and D. Bennett},
  journal={Neurology},
  year={2007},
  volume={69},
  pages={1911 - 1920}
}

R. Wilson, P. Scherr, +2 authors D. Bennett

Published 2007

Psychology, Medicine

Neurology

Background: Frequent cognitive activity in old age has been associated with reduced risk of Alzheimer disease (AD), but the basis of the association is uncertain. Methods: More than 700 old people underwent annual clinical evaluations for up to 5 years. At baseline, they rated current and past frequency of cognitive activity with the current activity measure administered annually thereafter. Those who died underwent a uniform postmortem examination of the brain. Amyloid burden, density of… CONTINUE READING

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