Relation of IL28B Gene Polymorphism with Biochemical and Histological Features in Hepatitis C Virus-Induced Liver Disease

@inproceedings{Agndez2012RelationOI,
  title={Relation of IL28B Gene Polymorphism with Biochemical and Histological Features in Hepatitis C Virus-Induced Liver Disease},
  author={Jos{\'e} A. G. Ag{\'u}ndez and Elena Garcia-Martin and Mar{\'i}a Luisa Maestro and Francisca Cuenca and Carmen Mart{\'i}nez and L. Ruiz Ortega and Miguel Carballo and Marta Vidaurreta and Marta Agreda and Gabriela D{\'i}az-Zelaya and Avelina Su{\'a}rez and Manuel D{\'i}az-Rubio and Jos{\'e} Mar{\'i}a Ladero},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND/AIMS Polymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chronic infection. Our aim was to study the influence of IL28B rs12979860 gene polymorphism on the biochemistry and pathology of HCV-induced disease in the clinical course from mild chronic hepatitis C to hepatocellular carcinoma. METHODS We have determined the rs12979860 single nucleotide polymorphism (SNP) upstream IL28B gene in two groups of patients with HCV-induced chronic liver disease: 1… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 56 references

Real time quantitative PCR.

View 2 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…