Relation between physicochemical properties of phenols and their toxicity and accumulation in fish.

@article{Saarikoski1982RelationBP,
  title={Relation between physicochemical properties of phenols and their toxicity and accumulation in fish.},
  author={Juhani Saarikoski and Matti Viluksela},
  journal={Ecotoxicology and environmental safety},
  year={1982},
  volume={6 6},
  pages={501-12}
}
The 96-hr LC50 values of 21 substituted phenols for the guppy (Poecilia reticulata) were determined at pH levels 6-8 and related to the lipophilicity defined as log P from the 1-octanol/water system, and to the delta pKa value (pKa of phenol-pKa). Log P was the more important parameter and exhibited a good correlation with log(1/LC50) at pH levels. The contribution of delta pKa when introduced as a second parameter into the regression equation was dependent on the pH of water: at pH 6 it was… CONTINUE READING

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