Relation between neutralization of Epstein-Barr virus and antibodies to cell-membrane antigens-induced by the virus.

@article{Pearson1970RelationBN,
  title={Relation between neutralization of Epstein-Barr virus and antibodies to cell-membrane antigens-induced by the virus.},
  author={G. R. Pearson and F Dewey and George Klein and Gertrude Henle and Werner Henle},
  journal={Journal of the National Cancer Institute},
  year={1970},
  volume={45 5},
  pages={989-95}
}
The neutralization of Epstein-Barr virus (EBV) infectivity by sera with known antibody activities against EBV-associated antigens was investigated in experimentally infected Raji and RPMI 64-10 cells. Antibodies against EBV-induced cell-membrane antigens were apparently responsible for neutralization of viral infectivity. Antibodies against EBV capsid antigens and EBV-induced early antigens were not involved. The implication of these results on the relationship of the membrane antigens to the… CONTINUE READING

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