Relation between medial temporal atrophy and functional brain activity during memory processing in Alzheimer's disease: a combined MRI and SPECT study.

@article{Garrido2002RelationBM,
  title={Relation between medial temporal atrophy and functional brain activity during memory processing in Alzheimer's disease: a combined MRI and SPECT study.},
  author={Griselda E. J Garrido and S{\'e}rgio Shiguemi Furuie and Carlos Alberto Buchpiguel and C{\'a}ssio M. C. Bottino and Osvaldo P. Almeida and Carla Garcia Cid and C{\^a}ndida Helena P. Camargo and Claudio Castro and Michael Francis Glabus and Geraldo F. Busatto},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2002},
  volume={73 5},
  pages={
          508-16
        }
}
OBJECTIVE To investigate the relation between atrophy of the hippocampal region and brain functional patterns during episodic memory processing in Alzheimer's disease. PATIENTS AND METHODS Whole brain structural magnetic resonance imaging (MRI) data and single photon emission computed tomography (SPECT) measures of regional cerebral blood flow (rCBF) were obtained during a verbal recognition memory task in nine subjects with mild Alzheimer's disease and 10 elderly healthy controls. Using the… CONTINUE READING

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