Relation between kidney function, proteinuria, and adverse outcomes.

  title={Relation between kidney function, proteinuria, and adverse outcomes.},
  author={Brenda R. Hemmelgarn and Braden J. Manns and Anita M Lloyd and Matthew T. James and Scott W. Klarenbach and Robert Ross Quinn and Natasha Wiebe and Marcello Tonelli},
  volume={303 5},
CONTEXT The current staging system for chronic kidney disease is based primarily on estimated glomerular filtration rate (eGFR) with lower eGFR associated with higher risk of adverse outcomes. Although proteinuria is also associated with adverse outcomes, it is not used to refine risk estimates of adverse events in this current system. OBJECTIVE To determine the association between reduced GFR, proteinuria, and adverse clinical outcomes. DESIGN, SETTING, AND PARTICIPANTS Community-based… CONTINUE READING
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