Relation between high energy phosphate and lethal injury in myocardial ischemia in the dog.

@article{Jennings1978RelationBH,
  title={Relation between high energy phosphate and lethal injury in myocardial ischemia in the dog.},
  author={Robert B. Jennings and Hal K. Hawkins and James E. Lowe and Marilyn L Hill and S Klotman and Keith A. Reimer},
  journal={The American journal of pathology},
  year={1978},
  volume={92 1},
  pages={187-214}
}
The relationship between progressive depletion of high energy phosphate and the onset of lethal cell injury in ischemic myocardium following coronary occlusion has been evaluated. Myocardial ischemia was induced by proximal occlusion of the circumflex coronary artery for 15, 30, 40, or 60 minutes. Cell injury in the severely ischemic posterior papillary muscle (PP) was evaluated by electron microscopy and by measuring the capacity of slices of the injured PP to maintain electrolytes… CONTINUE READING

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