Relation between functional polymorphism of catalase gene (-262C>T) and recurrent depressive disorder.

@article{Gaecki2009RelationBF,
  title={Relation between functional polymorphism of catalase gene (-262C>T) and recurrent depressive disorder.},
  author={Piotr Gaļecki and Janusz Szemraj and Krzysztof Zboralski and Antoni Florkowski and Andrzej Lewiński},
  journal={Neuro endocrinology letters},
  year={2009},
  volume={30 3},
  pages={357-62}
}
Numerous studies have provided information indicating the involvement of oxidative stress in the pathophysiology of depressive disorder (DD). The antioxidative system protects against the effects caused by reactive oxygen species (ROS). Catalase (CAT) is one of antioxidative enzymes observed to change their levels in the course of depression. The enzyme decomposes hydrogen peroxide (H(2)O(2)), whose overproduction is a result of many processes taking place in depression. Therefore, functional… CONTINUE READING