Relation between distribution of viral RNA and development of histopathological changes in encephalomyocarditis virus-induced orchitis in mice.

@article{Ueno1996RelationBD,
  title={Relation between distribution of viral RNA and development of histopathological changes in encephalomyocarditis virus-induced orchitis in mice.},
  author={Akinori Ueno and Makio Takeda and Ken-ichi Hirasawa and S I Itagaki and Kohei Doi},
  journal={International journal of experimental pathology},
  year={1996},
  volume={77 1},
  pages={25-30}
}
The relation between the distribution of viral RNA and the development of histopathological changes was investigated in the early stage of encephalomyocarditis (EMC) virus-induced orchitis in mice. Signals of viral RNA were first detected by in situ hybridization in a few Sertoli cells in almost intact germinal epithelia at 2 days post-inoculation (d.p.i.). The number of Sertoli cells bearing signals of viral RNA increased at 3 d.p.i. when mild degenerative changes were exceptionally found in… CONTINUE READING