Relation between carotid intima-media thickness, platelet surface activation and endothelial cell markers.

@article{Ramsis1998RelationBC,
  title={Relation between carotid intima-media thickness, platelet surface activation and endothelial cell markers.},
  author={N Ramsis and Ahmed A El-Hawary and Essadi Ismail},
  journal={Haemostasis},
  year={1998},
  volume={28 5},
  pages={268-75}
}
BACKGROUND The role of platelet activation and endothelial cell damage in the pathogenesis of atherosclerosis was investigated. METHODS Flow-cytometric detection of platelet activity was accomplished by measuring the surface expression of activated platelet glycoprotein IIb/IIIa (activated CD41) and the lysosomal integral membrane protein (CD63). Levels of thrombomodulin (TM) and von Willebrand factor (vWF) were estimated by the ELISA technique as markers of endothelial cell damage. These… CONTINUE READING