Relation between NT-proBNP levels, iron overload, and early stage of myocardial dysfunction in β-thalassemia major patients.

@article{Balkan2012RelationBN,
  title={Relation between NT-proBNP levels, iron overload, and early stage of myocardial dysfunction in β-thalassemia major patients.},
  author={C. Balkan and Selcen Yakar Tuluce and Gunes Basol and Kamil Tuluce and Yılmaz Ay and Deniz Yilmaz Karapinar and Cemil Gurgun and O. Dilek Bayindir and Kaan Kavakli},
  journal={Echocardiography},
  year={2012},
  volume={29 3},
  pages={
          318-25
        }
}
BACKGROUND Heart failure (HF) secondary to myocardial iron loading remains the leading cause of death in β-thalassemia major (β-TM) patients. The early diagnosis and treatment of HF in these patients is related to survival. We aimed to evaluate myocardial performance using conventional and tissue Doppler echocardiography and its relation to plasma NT-proBNP levels and iron overload indices in β-TM patients with preserved systolic function. METHODS The study population included 49 β-TM… CONTINUE READING
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