Relapsing tubulointerstitial nephritis in an adolescent with inflammatory bowel disease without aminosalicylate exposure.

@article{Muhammad2010RelapsingTN,
  title={Relapsing tubulointerstitial nephritis in an adolescent with inflammatory bowel disease without aminosalicylate exposure.},
  author={H S Shahrani Muhammad and Catherine Stollar Peters and Liam F. Casserly and Anthony M. Dorman and Matthew E. Watts},
  journal={Clinical nephrology},
  year={2010},
  volume={73 3},
  pages={
          250-2
        }
}
A 14-year-old boy presented with ongoing constipation as a manifestation of newly diagnosed Crohn's disease (CD) and a concomitant decline in renal function with biopsy-proven interstitial nephritis. Initiation of steroid therapy and mesalazine was associated with an improvement in symptoms and renal function. We describe a rare case of a 5-aminosalicylic acid (5-ASA)-naïve patient who developed interstitial nephritis in association with CD with no evidence of other primary glomerulopathy. A… CONTINUE READING
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