Relapsing autoimmune demyelination: a role for vascular addressins

  title={Relapsing autoimmune demyelination: a role for vascular addressins},
  author={Barbara A Cannella and Anne H. Cross and Cedric S Raine},
  journal={Journal of Neuroimmunology},
The expression of two vascular addressins, adhesion molecules implicated in lymphocyte traffic via high endothelial venules (HEV) within lymph node and mucosal tissues, and of an HEV differentiation antigen (Ag) has been followed immunocytochemically in the central nervous system (CNS) of SJL mice at different stages of adoptively-transferred, chronic relapsing experimental autoimmune encephalomyelitis (EAE). Monoclonal antibody (mAb), MECA-325, which defines an HEV cell differentiation Ag… CONTINUE READING

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