Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites.

  title={Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites.},
  author={Mallika Imwong and Georges Snounou and Sasithon Pukrittayakamee and Naowarat Tanomsing and Jung Ryong Kim and Amitab Nandy and J. G. Kirk A. W. Guthmann and François H Nosten and Jane M. Carlton and Sornchai Looareesuwan and Shalini K. Nair and Daniel W Sudimack and Nicholas P J Day and Timothy J. C. Anderson and Nicholas J. White},
  journal={The Journal of infectious diseases},
  volume={195 7},
BACKGROUND Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection. It has been assumed that parasites causing relapse would be a subset of the parasites that caused the primary infection. METHODS Paired samples were collected before initiation of antimalarial treatment and at recurrence of parasitemia from 149 patients with vivax malaria in Thailand (n=36… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 126 extracted citations

Evaluation of Plasmodium vivax genotyping markers for molecular monitoring in clinical trials.

The Journal of infectious diseases • 2009
View 4 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 28 references

Molecular analysis of Plasmodium vivax relapses using the MSP1 molecule as a genetic marker

K Kirchgatter, HA delPortillo
J Infect Dis • 1998
View 4 Excerpts
Highly Influenced

Meager genetic variability of the human malaria agent Plasmodium vivax.

Proceedings of the National Academy of Sciences of the United States of America • 2004

Identification of a polymorphic Plasmodium vivax microsatellite marker

JC Gomez
Am J Trop Med Hyg • 2003

Similar Papers

Loading similar papers…