Relapsed intracranial ependymoma in children in the UK: patterns of relapse, survival and therapeutic outcome.

@article{Messahel2009RelapsedIE,
  title={Relapsed intracranial ependymoma in children in the UK: patterns of relapse, survival and therapeutic outcome.},
  author={Boo Messahel and S. C. Ashley and Frank H. Saran and David Ellison and James Ironside and Kim Phipps and Tim Cox and William K Chong and Kath Robinson and Sue Picton and Charles Ross Pinkerton and Conor Mallucci and Donald Macarthur and Timothy Jaspan and Antony J. Michalski and Richard G. Grundy},
  journal={European journal of cancer},
  year={2009},
  volume={45 10},
  pages={1815-23}
}
Relapsed ependymoma in children poses difficult dilemmas in management. Clinico-pathological and treatment data of 108 children with relapsed ependymoma in the United Kingdom (UK) treated between 1985 and 2002 were reviewed to identify prognostic factors affecting survival. The primary site was the most common site of relapse (84%). Overall 25% had metastatic relapse. Surgery at relapse was attempted in only 55%. Radiotherapy was delivered at relapse in 66% infants and 50% of older children… CONTINUE READING