Relapse following discontinuation of antiepileptic drugs: a meta-analysis.

  title={Relapse following discontinuation of antiepileptic drugs: a meta-analysis.},
  author={Anne T. Berg and S Shinnar},
  volume={44 4},
The estimates in the literature of the risk of seizure relapse after antiepileptic medications are withdrawn range from less than 10% to nearly 70%. There is also little coherence regarding predictors of successful medication withdrawal. We performed a meta-analysis of the published literature to date to determine the risk of relapse at 1 and 2 years after discontinuation of medications and to examine the strength of association between the risk of relapse and three commonly assessed clinical… CONTINUE READING

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