RelA regulates the survival of activated effector CD8 T cells

Abstract

Nuclear factor of kappa B (NF-κB) transcription factors are critical regulators of T-cell activation and survival. The relative contribution of individual NF-κB members to these processes remains elusive. We investigated the role of RelA in the regulation of CD8 T-cell activation. We overexpressed, in mature CD8 T cells, a transactivation domain-deficient… (More)
DOI: 10.1038/sj.cdd.4401673

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