Rejection of reovirus-treated L1210 leukemia cells by mice

L1210 leukemia cells were treated in vitro with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and reovirus to determine their interactive effects on rejection of these tumor cells by mice. The cells were treated with BCNU at concentrations of 0, 3, or 10 μM, incubated for 48 h, then treated with reovirus at a multiplicity of infection of 0, 10, 30, or 100 for… CONTINUE READING