Rejection of marrow from DLA-identical canine littermates given transfusions before grafting: antigens involved are expressed on leukocytes and skin epithelial cells but not on platelets and red blood cells.

@article{Storb1979RejectionOM,
  title={Rejection of marrow from DLA-identical canine littermates given transfusions before grafting: antigens involved are expressed on leukocytes and skin epithelial cells but not on platelets and red blood cells.},
  author={Rainier Storb and Paul L. Weiden and H Joachim Deeg and Thomas Crofoot Graham and K A Atkinson and Sherrill J. Slichter and E. Donnall Thomas},
  journal={Blood},
  year={1979},
  volume={54 2},
  pages={477-84}
}
Previous studies in dogs given 1 200 R and a hemopoietic graft from DLA-identical littermates have shown that marrow graft rejection generally does not occur when the recipient is untransfused (58 of 59 achieved sustained engraftment) but is seen after a single transfusion of blood from the marrow donor on day -10 (13 of 18 rejected) and even after multiple transfusions of random blood (3 of 1 1 rejected). This study extends those initial observations by determining the incidence of rejection… CONTINUE READING