Reinstatement of cocaine place-conditioning prevented by the peptide kappa-opioid receptor antagonist arodyn.

Abstract

Stress contributes to the reinstatement of cocaine-seeking behavior in abstinent subjects. Kappa-opioid receptor antagonists attenuate the behavioral effects of stress, potentially providing therapeutic value in treating cocaine abuse. Presently, the peptide arodyn produced long-lasting kappa-opioid receptor antagonism, suppressing kappa-opioid receptor… (More)

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Cite this paper

@article{Carey2007ReinstatementOC, title={Reinstatement of cocaine place-conditioning prevented by the peptide kappa-opioid receptor antagonist arodyn.}, author={Alison F. Carey and K Borozny and Jane V Aldrich and Jay P. McLaughlin}, journal={European journal of pharmacology}, year={2007}, volume={569 1-2}, pages={84-9} }