Reinstatement of Morphine-Conditioned Reward is Blocked by Memantine

Abstract

Protection of abstinent individuals from relapse is the main goal of drug dependence treatment. Relapse is frequently precipitated by exposure to small doses of the drug of abuse or exposure to the environment that was previously associated with the drug. Mice exposed to morphine (10 mg/kg) in a unique test-box environment display a conditioned place… (More)
DOI: 10.1038/sj.npp.1300760

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