Reinitiation of meiosis in starfish oocytes requires an increase in nuclear Ca2+.

@article{Santella1994ReinitiationOM,
  title={Reinitiation of meiosis in starfish oocytes requires an increase in nuclear Ca2+.},
  author={Luigia Santella and Keiichiro Kyozuka},
  journal={Biochemical and biophysical research communications},
  year={1994},
  volume={203 1},
  pages={674-80}
}
Here we report that an increase in nuclear Ca2+ is hormonally regulated and is required for reinitiation of meiosis in starfish oocytes. We have shown in Asterina pectinifera that a Ca2+ transient and a baseline increase of Ca2+ occur both in the cytoplasm and in the nucleus. These increases are in response to 1-methyladenine (1-MA), the hormone responsible for the induction of meiotic maturation. The Ca2+ transients are not necessary for the reinitiation of meiosis. However, blocking the… CONTINUE READING

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